Hyalu sulfa

Mechanism of Action:

The cream improves the patient’s condition by performing the following functions:

• Works on the cell membrane and the cell wall and inhibits various bacterial

metabolic processes.

Indications:

This cream is indicated for the management of skin lesions, especially those at high risk of infection. In particular, it is intended to cover acute and chronic wounds (first and second-degree burns, vascular and metabolic ulcers and pressure sores) and to provide a moist microbe-free wound environment.

This cream can be used on non-infected wounds to help in preventing infection and, following successful treatment of infected wounds, to help prevent the reoccurrence of infection.

Contraindications:

• Acne
• Hypersensitivity
• Lactation
• Neonates

Porphyria

Pregnancy

Do not administer to patients with ascertained individual hypersensitivity to the product components or with liver or renal failure or glucose-6-phosphate

dehydrogenase deficiency.

Do not administer to pregnant women and to babies.

Side-effects:

• Rashes
• Sulfonamide induced systemic toxicity
• Interstitial inflammation of the kidneys

Allergic reactions

• Transient decrease in the number of white blood cells
• Skin discoloration
• Burning sensation
• Skin drying
• Death of cells
• renal failure, toxic hepatitis, agranulocytosis, thrombocytopenia, leukopeniaWarnings and Precautions:Discard after a month from the first opening.Avoid direct contact of the container with the wound.Each tube of the cream should be used by one patient only, in order to reduce the risk of cross infection.Avoid exposing treated areas to sunlight, as products containing silver sulfadiazine may stain skin brownish grey. Any staining can easily be removed by washing the

  area. Severe and extensive burns and ulcers must be treated under the supervision of a physician.

  Extensive or badly infected sores, such as those caused by bites and stings, need to be treated by a physician (risk of tetanus).

  It is advised to seek a physician in case the wound flaps are red, the wound is swollen and painful, and if the body temperature rises (risk of blood poisoning). Interactions:

  Do not use concomitantly with disinfectants containing quaternary ammonium salts or with locally applied proteolytic enzymes, because they can interact with the product. cream may interact with the following drugs and products:

  • Benzocaine

  Cetylpyridinium

  • Lidocaine

  Povidone-iodine

  • Sulfacetamide sodium
  • Tolbutamide Trimethoprim

  Dosage and Administration:

  The lesions should be cleansed prior to each application. Apply a thin layer of cream onto the wound surface, once or twice a day depending on the severity, until complete healing occurs. Prolonged treatments, over a month, should be assessed by a physician on the basis of the clinical evolution of the lesion. The treated area should be covered with a sterile bandage.

  Storage conditions:

  Keep out of reach of children.

  Store at room temperature, below 30°c, away from light.

  Use within 6 months after opening.

  Packaging:

  Aluminium tube contains 25 gram or 100 gram.